Dr.rer.nat. Solveigh Cornelia Koeberle
+43 316 380 - 5532
Institute of Pharmaceutical Sciences / Pharmacognosy
University of Graz
Beethovenstraße 8, A-8010 Graz, Austria
Room: 0111-03-0090
https://pharmazie.uni-graz.at/en/research/pharmacognosy/dr.-rer.-nat.-dipl.-pharm.-solveigh-koeberle
Dr. Solveigh Koeberle studied pharmacy and obtained her doctorate in medicinal chemistry at the University of Tübingen. After a two-year post-doctoral fellowship at the University of Tokyo (Cellular Neurobiology) and research stays at the Leibniz Institute on Aging (FLI Jena) and the University of Jena, she worked as Senior Lecturer in Pharmacognosy and Principal Investigator at the Michael Popp Institute in Innsbruck. From 2022 to 2024, she held an interim professorship in medicinal chemistry at the University of Regensburg. Her research, funded by the renowned Elise Richter Program of the Austrian Science Fund (FWF), focuses on the development of innovative drug candidates, the elucidation of molecular targets and disease mechanisms, and the exploration of novel therapeutic approaches for degenerative diseases such as metabolic-associated fatty liver disease (MAFLD), Alzheimer's and Parkinson's, with a particular focus on ferroptosis-inhibiting natural products.
Awards, fellowships and fundings
2025 Elise Richter Fellow (Austrian Science Fund FWF)
2019-2021 Grant of the Friedrich Schiller University Jena (Germany)
2016-2017 Fellowship of the Leibniz Institute on Aging Jena (Germany)
2014-2015 Fellowship of the Leibniz Institute on Aging Jena (Germany)
2009-2011 Fellowship of the „Deutsche Pharmazeutische Gesellschaft“(DPhG) / Pharmaceutical Society of Japan (PSJ) and of the Takeda Science Foundation for a 2-year research period at The University of Tokyo (Japan)
2005 Participation at the “55th meeting of Nobel laureates in Medicine, Chemistry, and Physics in Lindau” (Germany)
Memberships
Since 2004 Member of the German Pharmaceutical Society (DPhG)
Since 2009 Member of the Takeda Science Foundation
2010 Member of the “Japanese Society of Neuroscience”
Since 2018 Member of the Society of Minerals and Trace Elements (GMS)
Since 2020 Member of the Herbal Medicinal Products Platform Austria (HMPPA)
Since 2024 Board Member of the HMPPA
Since 2024 Member of the Society for Medicinal Plant and Natural Product Research (GA)
Since 2024 Member of theÖsterreichische Pharmazeutische Gesellschaft (OePHG)
Oral Presentations
Koeberle, S. (2025) Decoding Ferroptosis: Natural product inspired drug discovery in degenerative disease, Meeting of the European Federation of Pharmaceutical Science (EUFEPS) (Vienna, Austria)
Koeberle, S. (2024) Uncovering redox-regenerating agents to combat ferroptosis INVITED TALK (University of MCLouvain (UCL), Brussels, Belgium).
Koeberle, S. (2024) Uncovering redox-regenerating agents to combat ferroptosis, INVITED TALK at the Lecture Series Cancer Biology (Ludwig-Maximilians-Universität München, München, Germany).
Koeberle, S. (2024) Utilizing FSP1 Oxidoreductase for Efficient Redox Regeneration of Radical Scavengers in Ferroptosis Protection, INVITED TALK at the Lecutures Series of the PhD Student/PostDoc Seminar of the SPP2306 Priority Program " Ferroptosis: from Molecular Basics to Clinical Applications".
Koeberle, S. (2024) Utilising FSP1 Oxidoreductase for Efficient Redox Regeneration of Radical Scavengers in Ferroptosis Protection, Austrian Summit on Natural Products (Seefeld, Austria).
Koeberle, S. (2023) Hijacking endogenous redox cycles to mitigate ferroptoticcell death, Annual Meeting of the German Pharmaceutical Society (DPhG) (Tübingen, Germany).
Koeberle, S. (2023) Manipulating endogenous redox systems to protect against ferroptotic cell death, Oral presentation at the Seminar"Current Discoveries in Biomedical Research" (Innsbruck, Austria).
Koeberle, S. (2023) Targeting lipid metabolism at the crossroad of different cell death programmes, EMBO Workshop Ferroptosis: When metabolism meets cell death (Seeon- Seebruck, Germany).
Koeberle, S. (2022) To live or to die: Reprogramming cell fate with natural products, Meeting of the Center for Molecular Biosciences Innsbruck (CMBI) (Igls, Austria).
Koeberle, S. (2022) NRF2 cysteine code in ferroptosis and necroinflammation, INVITED TALK, Mini-Symposium: Michael Popp Institute, University of Innsbruck - German Cancer Research Center, Heidelberg. Cell death: metabolism, bioactive lipids and therapeutic strategies, VIRTUAL.
Koeberle, S. (2022) Selenium in NRF2 dependent redox signalling, INVITED TALK, International Conference of Trace Elements and Minerals (ICTEM) (Aachen, Germany).
Koeberle, S. (2021) Structural requirements of silybin fromSilybum marianumthat favourably shift fatty acids from triglycerides towards phospholipids in liver, INVITED TALK, HMPPA Symposium Milk Thistle: Phytochemical, pharmacological and clinical evidence, VIRTUAL.
Koeberle, S. (2021) Biogenic ferroptosis-modulating compounds: Challenges and opportunities in interfering with redox signalling and potential therapeutic applications, HMPPA Symposium "Next Generation in Pharmacognosy (Krems, Austria).
Koeberle, S. (2021) Redox-dependent regulation of inflammatory lipid mediator biosynthesis by glutathione peroxidases 1 and 2 as promising novel anti-inflammatory strategy, Highlight Talk, Annual Meeting of the German Pharmaceutical Society (DPhG), VIRTUAL.
Koeberle, S. (2021) The flavonolignan silybin from Silybum marianum targets hepatic lipid biosynthesis and elevates the hepatic biotransformation capacity, Society for Medicinal Plant and Natural Product Research (GA) Annual Meeting, VIDEO CONTRIBUTION.
Koeberle, S. (2021) Glutathione peroxidases 1 and 2 as promising targets in anti-inflammatory therapy, Highlight Talk, Meeting of the European Federation of Pharmaceutical Science (EUFEPS), VIRTUAL.
Koeberle, S. (2021) Glutathione peroxidases - Novel targets of anti-inflammatory drugs? Highlight Talk, Frontiers in Medicinal Chemistry, VIRTUAL.
Koeberle, S. (2021) Impact of the trace element selenium on macrophages during differentiation, Scientific Congress of the German Society of Nutrition (DGE), VIRTUAL.
Koeberle, S. (2020) Selenoproteins in redox-dependent inflammatory signalling, Seminar series "Current research results in Pharmacy" (University of Innsbruck, VIRTUAL).
Koeberle, S. (2012) Forgotten neuronal signalling mechanisms: Importance of contact-dependent processes in brain development, Leibniz Institute on Aging (Jena, Germany).
Koeberle, S. (2011) What is the role of the tumour suppressor gene NF2 in the brain during development? Leibniz Institute on Aging Evaluation (Jena, Germany).
Koeberle, S. (2011) Role of CaMKIIα activity in spine formation and morphology during development, INVITED TALK, Leibniz Institute on Aging (Jena, Germany).
Koeberle, S. (2010) Role of CaMKIIα activity in spine formation and dendritic arborisation during development, Joint Workshop, University of Tokyo, (Tokyo, Japan).
Koeberle, S. (2009) Synthesis and biological testing of new aza-analogue and disubstituted dibenzepinones as inhibitors of p38 MAP, University of Tübingen (Tübingen, Germany).
Koeberle, S. (2005) Synthesis of dibenzosuberone derivatives as allosteric p38 MAP kinase inhibitors, University of Tübingen (Tübingen, Germany).
Public Relation
2021 Contribution to the reorganization of the sector “Medicinal Plants” and “Agricultural Plants” of the Botanical Garden in Innsbruck
Peer review activities
- Nature (IF 64.8)
- Cancer Communications (IF 16.8)
- Theranostics (IF 12.4)
- British Journal of Pharmacology (IF 8.7)
- International Journal of Molecular Science (IF 6.2)
- Food and Chemical Toxicology (IF 5.6)
- BioMed Research International (IF 3.4)